Sakitamiwa Classification ((top)) Link

Ulcer shrinks; reddish regenerating epithelium appears at the borders

Regenerative epithelium (new skin-like tissue) begins to appear at the edges, making the ulcer shallower. The white coating starts to shrink.

Sakita-Miwa is considered superior for tracking long-term regeneration, whereas Forrest is critical for immediate emergency management. Conclusion sakitamiwa classification

The final stage of healing. The redness disappears, leaving a white, flat scar as fibrous tissue matures and capillary density decreases. Summary Table Clinical Feature Highlights Active Thick white coating, edema, discrete margins Healing Epithelial regeneration, shallower base, shrinking coating Scarring Complete closure; initially red, maturing into a white scar

Understanding this classification is essential for gastroenterologists, endoscopists, and clinical researchers evaluating the efficacy of acid-suppressive therapies like proton pump inhibitors (PPIs) and potassium-competitive acid blockers (P-CABs). The Three Major Macro-Stages Conclusion The final stage of healing

[A1: Acute Edema] ➔ [A2: Clear Margin] ➔ [H1: Epithelial Growth] ➔ [H2: Flat Crater] ➔ [S1: Red Scar] ➔ [S2: White Scar] Granular Breakdown of the Six Sakita-Miwa Stages 1. The Active Stage (A-Stage)

: Over a few weeks to months, the excess blood vessels regress. The redness fades completely, leaving behind a pale, white, or translucent fibrous scar. At stage S2, the ulcer is officially classified as endoscopically cured . Quantitative Scoring in Clinical Research The Three Major Macro-Stages [A1: Acute Edema] ➔

The Sakita-Miwa classification is a widely recognized endoscopic system used to stage the life cycle and healing process of peptic ulcers . It divides the ulcer's progression into three main stages—Active, Healing, and Scarring—each containing two sub-stages . Key Endoscopic Characteristics Active (A) A1